James Waite at NOVO Study Club talks about PRF technology

14.09.2025
Support for the military, collaboration between NOVO and the military hospital in Lviv, NOVO Medical Center

The visit of American physician and PRF technology specialist James Waite to NOVO Medical Center is a significant event for medical professionals, offering an opportunity to gain new knowledge and explore ways to apply cutting-edge techniques in Ukrainian medicine.

On September 12, as part of the NOVO Study Club educational programs, a lecture by the invited expert took place, during which Dr. Waite, using interactive technologies, shared valuable experience about the PRF method, which has gained popularity worldwide over the past 6-7 years.

PRF, or Platelet-Rich Fibrin, is produced from whole blood without the addition of anticoagulants. It must be centrifuged for 90 seconds after collection, before it begins to clot, to obtain a solid clot or liquid form.

Support for the military, collaboration between NOVO and the military hospital in Lviv, NOVO Medical Center

Before the event, James Waite visited NOVO Medical Center, where he familiarized himself with the latest MRI, CT, ultrasound, and endoscopic technologies used at the facility, which enable the Center’s specialists to conduct highly accurate examinations and provide patients with comprehensive diagnostic results.

The Medical Director of NOVO, Anzhela Dyba, informed the distinguished guest about the specifics of the Center’s operations, advanced treatment technologies, plans, prospects, and NOVO’s capabilities in implementing projects.

In turn, the Director of NOVO Medical Center, Taras Lysak, told James Waite about the Center’s charitable programs for socially vulnerable groups—children and adults—which the Center has been implementing for nearly 11 years, with an especially urgent need felt since the full-scale invasion of our country by the aggressor nation.

Support for the military, collaboration between NOVO and the military hospital in Lviv, NOVO Medical Center

During the lecture, Dr. Waite focused the attention of medical professionals on key aspects of his work in the USA:

  • Active factors in PRF and PRP technologies, their main effects, and significant differences between the methods;
  • Forms of PRF and methods of obtaining them;
  • Innovativeness of horizontal centrifugation;
  • Types of tubes used in PRF technologies;
  • Analytics regarding clot formation based on gender, age, geographic factors, and more.
Support for the military, collaboration between NOVO and the military hospital in Lviv, NOVO Medical Center

Due to the fact that the effect of PRF therapy lasts 10-14 days, compared to about two days for PRP, cells and factors remain highly concentrated thanks to the centrifugation process and are recruited throughout the time the clot is active.

Solid clots can be pressed into membranes, cut into individual shapes, divided into parts, and mixed with bone fragments, placed under incisions, used to fill defects or tooth extraction sites with or without added bone.

Liquid PRF can be injected along incisions, administered via injection or microneedling for facial rejuvenation and even hair regrowth, injected into joints or other tissues, added to bone grafts, and allowed to clot to improve the efficiency and characteristics of implant processing.

Support for the military, collaboration between NOVO and the military hospital in Lviv, NOVO Medical Center

Horizontal centrifugation in the application of the PRF technique is more effective than fixed-angle centrifugation.

When a horizontal centrifuge begins to spin, the tube holders rise until they are horizontal, perpendicular to the motor axis and the vector of centrifugal force. Cells are not pressed against the tube walls and can freely flow and separate according to their density. Horizontal separation can lead to a fourfold accumulation of cells in the PRF layer.

The size of the clot is determined by the tubes, not the specific centrifugation device, and can vary by 200% depending on the tube manufacturer.

Tubes must be removed and the centrifugation cycle started within 90 seconds, as the clot volume decreases by 13% after this time and by 23% after 120 seconds.

Support for the military, collaboration between NOVO and the military hospital in Lviv, NOVO Medical Center

According to Dr. James Waite’s research, women tend to form larger clots than men, by approximately 17%.

Additionally, individuals aged 61–80 are more prone to forming larger clots.

People living at higher altitudes have a higher hematocrit and may require 25% more centrifugation time.

Blood processing for individuals taking anticoagulants is performed the same way as for others, but their blood clotting takes longer.

Support for the military, collaboration between NOVO and the military hospital in Lviv, NOVO Medical Center

We thank James Waite for his significant contributions to medicine and for the opportunity to share valuable experience with Ukrainian colleagues through the educational programs organized by NOVO Study Club!

This is the first significant step in fruitful collaboration to help people using cutting-edge technologies!

Specialists from NOVO Medical Center and their colleagues from other medical institutions in Lviv have gained extremely valuable experience with the PRF technique. There is significant work ahead in implementing the acquired knowledge in practice. We believe that this additional step in helping people will yield qualitatively valuable results!

Yuliia Huryi (based on articles by James Waite)

Photos by Roman Metelskyi, Hlib Drach

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